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&lt;h1 id=&quot;cc-m-16339808225&quot; class=&quot;j-module n j-header &quot;&gt;&lt;strong&gt;Stages of Syphilis&lt;/strong&gt;&lt;/h1&gt;
&lt;div id=&quot;cc-m-14685615725&quot; class=&quot;j-module n j-hr &quot;&gt;&lt;hr /&gt;&lt;/div&gt;
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&lt;h2 class=&quot;HwSubSectionTitle &quot;&gt;&lt;strong&gt;Primary stage&lt;/strong&gt;&lt;/h2&gt;
&lt;p&gt;During the primary stage, a sore (&lt;a href=&quot;https://www.pulse-clinic.com.sg/syphilis&quot;&gt;chancre&lt;/a&gt;) that is usually painless develops at the site where the bacteria enter the body. This commonly occurs within 3 weeks of exposure but can range from 10 to 90 days. A person is highly contagious during the primary stage.&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;In men, a chancre often appears in the genital area, usually (but not always) on the penis. These sores are often painless.&lt;/li&gt;
&lt;li&gt;In women, chancres can develop on the outer genitals or the inner part of the vagina. A chancre may go unnoticed if it occurs inside the vagina or at the opening to the uterus (cervix) because the sores are usually painless and are not easily visible.&lt;/li&gt;
&lt;li&gt;Swelling of the&amp;nbsp;&lt;span class=&quot;HwLinkText&quot;&gt;lymph nodes&lt;/span&gt;&amp;nbsp;may occur near the area of the chancre.&lt;/li&gt;
&lt;li&gt;A chancre may also occur in an area of the body other than the genitals.&lt;/li&gt;
&lt;li&gt;The chancre lasts for 3 to 6 weeks, heals without treatment, and may leave a thin scar. But even though the chancre has healed, syphilis is still present and a person can still pass the infection to others.&lt;/li&gt;
&lt;/ul&gt;
&lt;h3 class=&quot;HwSubSectionTitle &quot;&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h2 class=&quot;HwSubSectionTitle &quot;&gt;&lt;strong&gt;Secondary stage&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;Secondary syphilis is characterized by a rash that appears from 2 to 8 weeks after the chancre develops and sometimes before it heals. Other symptoms may also occur, which means that the infection has spread throughout the body. A person is highly contagious during the secondary stage.&lt;/p&gt;
&lt;p&gt;A rash often develops over the body and commonly includes the palms of the hands and the soles of the feet.&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;The rash usually consists of a reddish brown, small, solid, flat, or raised skin sore or sores that are less than&amp;nbsp;&lt;span class=&quot;Measurement&quot;&gt;2 cm (0.8 in.)&lt;/span&gt;&amp;nbsp;across. The rash may look like other, more common skin problems.&lt;/li&gt;
&lt;li&gt;Small, open sores may be present on&amp;nbsp;&lt;span class=&quot;HwLinkText&quot;&gt;mucous membranes&lt;/span&gt;. The sores may contain pus, or moist sores that look like warts may be present (condyloma lata).&lt;/li&gt;
&lt;li&gt;In dark-skinned people, the sores may be a lighter color than the surrounding skin.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;The skin rash usually heals without scarring within 2 months. After healing, skin discoloration may develop. But even though the skin rash has healed, syphilis is still present, and a person can still pass the infection on to others.&lt;/p&gt;
&lt;p&gt;When syphilis has spread throughout the body, the person may have:&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;A fever is usually less than&amp;nbsp;&lt;span class=&quot;Measurement&quot;&gt;101&amp;deg;F (38&amp;deg;C)&lt;/span&gt;.&lt;/li&gt;
&lt;li&gt;A sore throat.&lt;/li&gt;
&lt;li&gt;A vague feeling of weakness or discomfort throughout the body.&lt;/li&gt;
&lt;li&gt;Weight loss.&lt;/li&gt;
&lt;li&gt;Patchy hair loss, especially in the eyebrows, eyelashes, and scalp hair.&lt;/li&gt;
&lt;li&gt;Swelling of the lymph nodes.&lt;/li&gt;
&lt;li&gt;Nervous system symptoms of secondary syphilis, which can include neck stiffness, headaches, irritability, paralysis, unequal reflexes, and irregular pupils.&lt;/li&gt;
&lt;/ul&gt;
&lt;h2 class=&quot;HwSubSectionTitle &quot;&gt;&amp;nbsp;&lt;/h2&gt;
&lt;h2 class=&quot;HwSubSectionTitle &quot;&gt;&lt;strong&gt;Latent (hidden) stage&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;If untreated, an infected person will progress to the latent (hidden) stage of syphilis. After the secondary-stage rash goes away, the person will not have any symptoms for a time (latent period). The latent period may be as brief as 1 year or range from 5 to 20 years.&lt;/p&gt;
&lt;p&gt;Often during this stage, an accurate diagnosis can only be made through blood testing, the person&#39;s history, or the birth of a child with&amp;nbsp;&lt;a href=&quot;https://www.uofmhealth.org/health-library/hw195492#hw195492-sec&quot; data-hwid=&quot;hw195492&quot;&gt;congenital syphilis&lt;/a&gt;.&lt;/p&gt;
&lt;p&gt;A person is contagious during the early part of the latent stage and may be contagious during the latent period when no symptoms are present.&lt;/p&gt;
&lt;h3 class=&quot;HwSubSectionTitle &quot;&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h2 class=&quot;HwSubSectionTitle &quot;&gt;&lt;strong&gt;Relapses of secondary syphilis&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;About 20 to 30 out of 100 people with syphilis have a relapse of the secondary stage of syphilis during the latent stage. A relapse means the person had passed through the second stage, had no &lt;a href=&quot;https://www.pulse-clinic.com.sg/syphilis&quot;&gt;syphilis symptoms&lt;/a&gt;, and then began to experience secondary-stage symptoms again. Relapses can occur several times.&lt;/p&gt;
&lt;p&gt;When relapses no longer occur, a person is not contagious through contact. However, a woman in the latent stage of syphilis may still pass the disease to her developing baby and may have a miscarriage, a stillbirth, or give birth to a baby infected with congenital syphilis.&lt;/p&gt;
&lt;h3 class=&quot;HwSubSectionTitle &quot;&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h2 class=&quot;HwSubSectionTitle &quot;&gt;&lt;strong&gt;Tertiary (late) stage&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;This is the most destructive stage of syphilis. If untreated, the tertiary stage may begin as early as 1 year after infection or at any time during a person&#39;s lifetime. A person may never experience this stage of the illness.&lt;/p&gt;
&lt;p&gt;The symptoms of tertiary (late) syphilis depend on the complications that occur. Complications of this stage include:&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Gummata, which are large sores inside the body or on the skin.&lt;/li&gt;
&lt;li&gt;Cardiovascular syphilis, which affects the heart and blood vessels.&lt;/li&gt;
&lt;li&gt;Neurosyphilis, which affects the nervous system.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
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