&lt;p style=&quot;text-indent: 0px; margin: 0px; text-align: left;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://cms.pulse-clinic.com/pulseteam/2&quot;&gt;Dr.Deyn Natthakhet Yaemim (Founding Director)&lt;/a&gt;&lt;/strong&gt; &lt;span style=&quot;color: #999999;&quot;&gt;6 June 2016, last updated 24 August 2022&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;text-indent: 0px; margin: 0px; text-align: center;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h1 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;PEP (Emergency PEP)&lt;/strong&gt;&lt;/h1&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;text-decoration: underline; color: #000000;&quot;&gt;&lt;strong&gt;Key Points&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PEP treatment involves taking anti-HIV drugs for 28 days after possible exposure to HIV.&lt;/li&gt;
&lt;li&gt;Before prescribing PEP, doctors will assess your risk of HIV infection.&lt;/li&gt;
&lt;li&gt;PEP is available at sexual health clinics as well as accident &amp;amp; emergency departments.&lt;/li&gt;
&lt;li&gt;We recommend the ned medication called KOCITAF.&lt;/li&gt;
&lt;/ul&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #000000;&quot;&gt;&lt;a href=&quot;https://www.pulse-clinic.com.sg/hiv-pep&quot;&gt;HIV PEP&lt;/a&gt; has to be taken within the first 72 hours after exposure. If you have a high risk, you should start PEP immediately.&lt;/span&gt;&lt;br /&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The sooner PEP is taken the more effective it is. Taking PEP within the first 24 hours PEP has been proven by years of studies to be able to reduce the chance of HIV transmission.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;If you are at high risk due to any of these factors, you may need to seek PEP:&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;ul style=&quot;list-style-type: square;&quot;&gt;
&lt;li&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;You have an HIV-positive partner who is not on treatment.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;You had anal/vaginal penetrative sex without a condom&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Condom broke or leaked during the intercourse&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Bleeding&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Having cuts or ulcers&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #000000;&quot;&gt;Y&lt;span style=&quot;font-weight: 400;&quot;&gt;ou&amp;rsquo;re uncircumcised&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #000000;&quot;&gt;You were exposed to potentially HIV-infected body fluids&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;You were exposed to HIV less than 72 hours ago.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;You have a sex partner with a high risk (for example, men who have sex with men or they are from Africa or SEA).&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;You have had sex with penetration not knowing of their status.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;If more than 72 hours have passed, even if it has been almost a week since the exposure, do seek a doctor for consultation and treatment. Primarily, the healthcare provider may assign 3-drug antiviral combinations if you become HIV-positive. You could minimize the damage the virus may cause to your immune system. &lt;/span&gt;&lt;/p&gt;
&lt;h2 style=&quot;-qt-paragraph-type: empty; -qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/h2&gt;
&lt;h3 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;What is the mechanism of Emergency PEP?&lt;/strong&gt;&lt;/h3&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;After exposure, HIV takes 2-3 days to settle in the human body&lt;/strong&gt;. You&amp;rsquo;ll always be HIV-positive if you get infected. If PEP is taken in time, it can help prevent the virus from growing, it will die out before spreading further. PEP helps the immune system so the infected cells won&amp;rsquo;t replicate the virus and die naturally not so long after.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;Is Emergency PEP 100% Effective?&lt;/strong&gt;&lt;/h3&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;PEP cannot cure HIV but it can prevent the virus from establishing in the body if taken in time. Most people who took PEP within the right time span after exposure to HIV don&amp;rsquo;t get infected. &lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3 style=&quot;text-indent: 0px; margin: 0px; text-align: center;&quot;&gt;&lt;iframe src=&quot;//www.youtube.com/embed/vVXzGpfyiFQ&quot; width=&quot;560&quot; height=&quot;314&quot; allowfullscreen=&quot;allowfullscreen&quot;&gt;&lt;/iframe&gt;&lt;/h3&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;Is it too late if you&amp;rsquo;re already exposed to HIV?&lt;/strong&gt;&lt;/h3&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;It can be stopped if you act fast. HIV needs a little time before it spreads and stays forever in the body. If the patient gets to PEP fast enough (in 72 hours), there&#39;s a high chance the body can get rid of the virus successfully.&lt;/span&gt;&lt;/p&gt;
&lt;h3 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;I won&amp;rsquo;t become HIV-positive if I take PEP?&lt;/strong&gt;&lt;/h3&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Research has proven that PEP drastically reduces the chance of being infected with HIV. However, PEP isn&amp;rsquo;t 100%. Some people become HIV-positive even after taking PEP. The reasons for the cases that lead to PEP not working could be:&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #000000;&quot;&gt;It&amp;rsquo;s been too long after the exposure &lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;text-indent: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;t&lt;span style=&quot;font-weight: 400;&quot;&gt;he patient skips doses. PEP needs to be taken every day for 28 days.&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #000000;&quot;&gt;A rare case of the patient developing anti-HIV drug resistance resulting in some strains of HIV not being able to be treated with certain PEP*&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;text-indent: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;HIV &lt;span style=&quot;color: #000000;&quot;&gt;has already developed too far in the body for PEP to stop the virus&lt;/span&gt;&lt;/span&gt;**&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #000000;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Having more exposure to HIV while taking PEP&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p style=&quot;-qt-paragraph-type: empty; -qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;WHAT WOULD BE DONE WHEN RECEIVING EMERGENCY PEP AT PULSE CLIN&lt;span style=&quot;color: #000000;&quot;&gt;IC?&lt;/span&gt;&lt;/strong&gt;&lt;/h3&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;1. Consultation&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;2. Rapid screening for HIV, Hepatitis B virus with results in 15 minutes, accuracy 99.9%&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;3. Kidney function tests&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;4. PEP Medications&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;5. Test or treatment for possible sexually transmitted infections&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-paragraph-type: empty; -qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;WHAT HIV PEP DRUGS DO WE USE?&lt;/strong&gt;&lt;/h3&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;We offer the most advanced PEP medicines with few side effects and effective HIV prevention to be taken for 28 days.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;For adults,&amp;nbsp;&lt;span style=&quot;font-weight: 400;&quot;&gt;Tenofovir paired with either Tenofovir (TDF) or emtricitabine (FTC) is the preferred combination to treat HIV. &lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;&lt;strong&gt;The 3rd drug will be assigned by the doctor. It&amp;rsquo;ll be another HIV medicine recommended by WHO and CDC.&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-paragraph-type: empty; -qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-paragraph-type: empty; -qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;If you happen to acquire the type of HIV that causes resistance, traditional HIV drugs won&amp;rsquo;t work. Therefore, some doctors recommend using advanced medicines because they can be effective against resistant strains. Those high-class medicines are available at our clinic and are more expensive than regular PEP. The doctor will prescribe the premium PEP if your risk is high based on your evaluation.&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-paragraph-type: empty; -qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;Are there other tasks that should be done?&lt;/strong&gt;&lt;/h3&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Patients might as well receive treatment for possible gonorrhoea, chlamydia, or syphilis. At PULSE Clinic, we offer PCR28, a test that can detect 28 infections in one go.&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;YOU DON&#39;T NEED PEP IF...&lt;/strong&gt;&lt;/h3&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;- &lt;span style=&quot;font-weight: 400;&quot;&gt;Your partner has got tested and is HIV-negative&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;- &lt;span style=&quot;font-weight: 400;&quot;&gt;Your partner has HIV but was treated and has the status &amp;lsquo;undetectable viral load&#39;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;-&amp;nbsp;You get bitten&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;span style=&quot;color: #000000;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;-&amp;nbsp;Semen of others gets in your eyes&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;

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