&lt;p style=&quot;text-indent: 0px; margin: 0px; text-align: center;&quot;&gt;Written by &lt;a href=&quot;https://cms.pulse-clinic.com/pulseteam/2&quot;&gt;Dr.Deyn Natthakhet Yaemim (Founding Director)&lt;/a&gt; on 6 June 2016, last updated 11 November 2024&lt;/p&gt;
&lt;hr /&gt;
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&lt;h1 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;PEP FAQ - Frequently Asked Questions about Emergency PEP&lt;/h1&gt;
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&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;If you&#39;ve had a high-risk exposure to HIV in the last 72 hours, PEP should be started as soon as possible. It is most effective when begun within 24 hours, so the sooner you start PEP, the better the protection.&lt;/p&gt;
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&lt;h2 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;Factors that may increase the risk of HIV infection, making you a potential candidate for PEP&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;ul style=&quot;list-style-type: square;&quot;&gt;
&lt;li&gt;The partner is known to be HIV positive AND is not on treatment.&lt;/li&gt;
&lt;li&gt;Anal sex with penetration without a condom&lt;/li&gt;
&lt;li&gt;Vaginal sex without a condom&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/condom-broke-in-bangkok-thailand-get-emergency-pep&quot;&gt;Condom break&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;Presence of blood&lt;/li&gt;
&lt;li&gt;Presence of cuts or ulcers&lt;/li&gt;
&lt;li&gt;You are not circumcised&lt;/li&gt;
&lt;li&gt;You have been exposed to potentially HIV-infected body fluids&lt;/li&gt;
&lt;li&gt;Your exposure was less than 72 hours ago&lt;/li&gt;
&lt;li&gt;Partner of unknown HIV status who belongs to a higher-risk HIV group (e.g. MSM or from Africa or S.E.Asia)&lt;/li&gt;
&lt;li&gt;They penetrated you (Their penis, your arse) AND you don&#39;t know for sure whether they have HIV or not.&lt;/li&gt;
&lt;/ul&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;If you can&#39;t access PEP within 72 hours but it&#39;s been 5-7 days since the exposure, it&#39;s still important to seek medical advice to discuss your options. This may include starting a 3-drug combination of antiretroviral medications as soon as possible, in case you&#39;ve contracted HIV. Early treatment can help reduce potential damage to your immune system.&lt;/p&gt;
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&lt;h2 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;What is PEP?&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;PEP, or Post-Exposure Prophylaxis, is a treatment aimed at preventing HIV infection in individuals who are HIV-negative and may have been exposed to the virus. By taking PEP, a person uses antiretroviral medications to stop HIV from establishing itself in the body.&lt;/p&gt;
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&lt;p style=&quot;text-indent: 0px; margin: 0px; text-align: center;&quot;&gt;&lt;strong&gt;For more information about the medication and ordering process, &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-indent: 0px; margin: 0px; text-align: center;&quot;&gt;&lt;strong&gt;please email&amp;nbsp;&lt;a href=&quot;mailto:info.silom@pulse-clinic.com&quot;&gt;pulseliving@pulse-clinic.com&lt;/a&gt;&amp;nbsp;or chat on your preferred platform.&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
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&lt;p style=&quot;text-align: center;&quot;&gt;&lt;strong&gt;&amp;nbsp;&lt;a href=&quot;https://wa.me/66842262569&quot;&gt;&lt;img src=&quot;https://cms.pulse-clinic.com/Files/WhatsApp.png&quot; width=&quot;48&quot; height=&quot;82&quot; /&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;span class=&quot;w-30 inline-block px-2 md:px-4 mt-3&quot;&gt;+66-84-226-2569&lt;/span&gt;&lt;/span&gt;&lt;/a&gt;&amp;nbsp; &amp;nbsp;&amp;nbsp;&lt;/strong&gt;&lt;strong&gt;&lt;a href=&quot;https://lin.ee/32kmr2VS&quot;&gt;&lt;img src=&quot;https://cms.pulse-clinic.com/Files/line-logo.png&quot; width=&quot;50&quot; height=&quot;85&quot; /&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;span class=&quot;w-30 inline-block px-2 mt-3&quot;&gt;@pulserx&amp;nbsp;&lt;/span&gt;&lt;/span&gt;&lt;/a&gt;&amp;nbsp; &amp;nbsp; &amp;nbsp; &amp;nbsp;&lt;/strong&gt;&lt;strong&gt;&lt;a href=&quot;weixin://dl/chat?pulseclinic&quot;&gt;&lt;img src=&quot;https://cms.pulse-clinic.com/Files/WeChat_App_Icon.png&quot; width=&quot;50&quot; height=&quot;85&quot; /&gt;&amp;nbsp;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;span class=&quot;w-30 inline-block px-2 mt-3&quot;&gt;PulseClinic&lt;/span&gt;&lt;/span&gt;&lt;/a&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: center;&quot;&gt;&amp;nbsp;&lt;/p&gt;
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&lt;h2 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;How does PEP work?&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;After exposure to HIV, it takes several days for the virus to establish itself in the body. Once established, HIV remains in the body for life. However, if you start PEP in time, the antiretroviral medications can stop the virus from reproducing. This prevents the HIV that&amp;rsquo;s already in your body from multiplying, allowing it to die off before it spreads. PEP helps the immune system block the virus from replicating within infected cells, causing those cells to die naturally without producing more copies of HIV.&lt;/p&gt;
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&lt;h2 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;How well does PEP work?&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;The optimal window for starting PEP is within 72 hours of potential HIV exposure, and it is highly effective if initiated within this time frame. PEP can prevent HIV infection, regardless of how the exposure occurred. However, it must be taken daily for at least 28 days, with each dose taken at the same time every day. This consistent dosing is crucial for ensuring the full effectiveness of the medication.&lt;/p&gt;
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&lt;h2 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;Is PEP for me?&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;PEP is the right tool for you to use to prevent yourself from getting HIV if&amp;nbsp;&amp;nbsp;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;text-indent: 0px;&quot;&gt;you&amp;rsquo;re HIV-negative or don&amp;rsquo;t know your HIV status&lt;/li&gt;
&lt;li style=&quot;text-indent: 0px;&quot;&gt;you may have been exposed to HIV during sex (for example, if the condom broke) within the last 72 hours&amp;nbsp;&lt;/li&gt;
&lt;li style=&quot;text-indent: 0px;&quot;&gt;you shared needles with someone else within the last 72 hours&lt;/li&gt;
&lt;li style=&quot;text-indent: 0px;&quot;&gt;you were sexually assaulted&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3 style=&quot;text-indent: 0px; margin: 0px; text-align: center;&quot;&gt;&lt;iframe src=&quot;//www.youtube.com/embed/vVXzGpfyiFQ&quot; width=&quot;560&quot; height=&quot;314&quot; allowfullscreen=&quot;allowfullscreen&quot; data-mce-fragment=&quot;1&quot;&gt;&lt;/iframe&gt;&lt;/h3&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;But if HIV is already in the body, isn&#39;t it too late?&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;Not if you act fast. Once HIV enters the bloodstream, it takes time before it permanently establishes itself in the body. If someone who has been exposed to HIV seeks PEP treatment quickly (within 72 hours), they have a good chance of preventing the virus from taking hold in their system.&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3 style=&quot;-qt-paragraph-type: empty; -qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h2 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;If I take PEP, I won&#39;t become HIV-positive?&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;Research shows that taking PEP greatly reduces the risk of HIV infection, but it does not offer 100% protection, and some people may still contract HIV even while on treatment. PEP can fail for several reasons:&lt;/p&gt;
&lt;p&gt;- The person doesn&amp;rsquo;t take the medication as prescribed (daily for a month) or is unable to complete the full course.&lt;br /&gt;- Some strains of HIV are resistant to certain antiretroviral drugs (though this is rare).&lt;br /&gt;- The initial viral load (amount of HIV in the body) is too high for the medication to be effective.&lt;/p&gt;
&lt;p&gt;However, the sooner PEP is started after exposure, the higher the chances of it being successful.&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
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&lt;h2 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;What would be done when receiving emergency PEP at PULSE Clinic?&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;1. Consultation&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;2. Rapid screening for HIV, Hepatitis B virus with results in 15 minutes, accuracy of 99.9%&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;3. Kidney function tests&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;4. PEP Medications&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;5. Test or treatment for possible sexually transmitted infections&lt;/p&gt;
&lt;p style=&quot;-qt-paragraph-type: empty; -qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
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&lt;h2 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;What HIV PEP drugs do we use?&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;We use the latest, gold-standard PEP medications that have fewer side effects and offer better HIV prevention. These medications are taken for a 28-day course.&lt;/p&gt;
&lt;p&gt;For adults, the preferred combination includes Tenofovir along with either Tenofovir Disoproxil Fumarate (TDF) and Emtricitabine (FTC), which are also the first-line drugs for HIV treatment.&lt;/p&gt;
&lt;p&gt;Your doctor will choose the third drug based on current guidelines from the WHO and CDC, which recommend it as a preferred option for HIV treatment.&lt;/p&gt;
&lt;p&gt;Some clients may not fully understand the concept of HIV drug resistance. In the rare event that you are exposed to a drug-resistant strain of HIV, standard PEP medications may not be effective. That&amp;rsquo;s why the CDC recommends using a higher class of medications for PEP, which are less likely to be affected by resistant strains of HIV. These medications are available at our clinics but come at a higher cost, significantly more than the standard PEP drugs used in lower-income countries. If your doctor prescribes these more expensive medications, it is because they&amp;rsquo;ve assessed that your risk is very high and are aiming to meet the high standards outlined in the CDC&amp;rsquo;s PEP treatment guidelines.&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
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&lt;h2 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;What else should be done?&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;At PULSE CLINICS, your doctor may recommend treatment to prevent potential infections like gonorrhea, chlamydia, or syphilis if you&#39;ve had unprotected sex or experienced a sexual incident. They will also suggest screening for STIs such as &lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/ureaplasma-parvum&quot;&gt;Ureaplasma parvum&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;, Ureaplasma urealyticum, &lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/mycoplasma-hominis&quot;&gt;Mycoplasma hominis&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;, &lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/mycoplasma-genitalium&quot;&gt;Mycoplasma genitalium&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;, &lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/trichomoniasis&quot;&gt;Trichomonas vaginalis&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;, and &lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/lgv-lymphogranuloma-venereum-treatment-in-thailand&quot;&gt;LGV&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;, as up to 70% of infections can be asymptomatic, meaning individuals may spread the infection without knowing. While it&#39;s commonly believed that &lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/sexually-transmitted-diseases-stds-in-thailand&quot;&gt;STDs/STIs&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt; are only transmitted through sexual contact, this is no longer the case in 2021. Many STDs/STIs can also spread through direct skin-to-skin contact, such as touching.&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-paragraph-type: empty; -qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2 style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;You don&#39;t need PEP if:&lt;/strong&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;- You are confident that your partner doesn&#39;t have HIV.&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;- The partner is HIV positive and on successful treatment (Known as &amp;lsquo;undetectable viral load&#39;)&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;- Human bites&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;- Another person&#39;s semen gets in your eye.&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3 style=&quot;text-align: center;&quot;&gt;&lt;strong&gt;Book Your Appointment Today!&lt;/strong&gt;&lt;/h3&gt;
&lt;h1 style=&quot;text-align: center;&quot;&gt;&lt;a href=&quot;https://www.pulse-health.org/booking&quot;&gt;&lt;strong&gt;&lt;img src=&quot;https://cms.pulse-health.org/Files/Buttons/EN-Booking-an-appointment-at-PULSE-Health.png&quot; width=&quot;300&quot; height=&quot;33&quot; /&gt;&lt;/strong&gt;&lt;/a&gt;&lt;/h1&gt;
&lt;p style=&quot;text-align: center;&quot;&gt;&lt;strong&gt;Contact us at&amp;nbsp;&lt;a href=&quot;mailto:info.bkk@pulse-clinic.com&quot;&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;info.bkk@pulse-clinic.com&lt;/span&gt;&lt;/a&gt; or chat on your preferred platform:&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: center;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://wa.me/66652371936&quot;&gt;&lt;img src=&quot;https://cms.pulse-clinic.com/Files/WhatsApp.png&quot; width=&quot;48&quot; height=&quot;82&quot; /&gt;&amp;nbsp;&lt;/a&gt;&lt;/strong&gt;&lt;strong&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;a href=&quot;https://wa.me/66652371936&quot;&gt;+66 65 237 1936&lt;/a&gt;&amp;nbsp;&lt;/span&gt;&amp;nbsp;&amp;nbsp;&lt;/strong&gt;&lt;strong&gt;&lt;a href=&quot;line://ti/p/@946svqfh&quot;&gt;&lt;img src=&quot;https://cms.pulse-clinic.com/Files/line-logo.png&quot; width=&quot;50&quot; height=&quot;85&quot; /&gt; &lt;span class=&quot;w-30 inline-block px-2 mt-3&quot;&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt; @PULSEClinic&lt;/span&gt;&lt;/span&gt;&lt;/a&gt;&amp;nbsp; &lt;/strong&gt;&lt;strong&gt;&lt;a href=&quot;weixin://dl/chat?pulseclinic&quot;&gt;&lt;img src=&quot;https://cms.pulse-clinic.com/Files/WeChat_App_Icon.png&quot; width=&quot;50&quot; height=&quot;85&quot; /&gt;&lt;/a&gt;&amp;nbsp;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;a href=&quot;weixin://dl/chat?pulseclinic&quot;&gt;&lt;span class=&quot;w-30 inline-block px-2 mt-3&quot;&gt;PulseClinic&lt;/span&gt;&lt;/a&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: center;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;text-align: center;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;text-align: center;&quot;&gt;&amp;nbsp;&lt;/p&gt;

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