&lt;h1 class=&quot;heading-title&quot;&gt;&lt;a title=&quot;Frequent ejaculation associated free radical and lactic acid accumulation cause noninfectious inflammation and muscle dysfunction: a potential mechanism for symptoms in Chronic Prostatitis/Chronic Pelvic Pain Syndrome&quot; href=&quot;https://pubmed.ncbi.nlm.nih.gov/19435656/&quot;&gt;Frequent ejaculation associated free radical and lactic acid accumulation cause noninfectious inflammation and muscle dysfunction: a potential mechanism for symptoms in Chronic Prostatitis/Chronic Pelvic Pain Syndrome&lt;/a&gt;&lt;/h1&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;During male ejaculation, the pelvic muscles undergo coordinated intense contraction to expel the semen out of the male genital tract, a process associated with locally increased levels of lactic acid and free radicals as byproducts. In this regards, repetitive sexual activities with frequent ejaculation would impede the drainage and cause accumulation of these byproducts in the pelvic region, triggering consequent local pathophysiological changes such as edema, venous dilation and muscular malfunction, which further leads to common complaints in Chronic Prostatitis (CP)/Chronic Pelvic Pain Syndromes (CPPS). patients such as lower urinary tract symptoms, pelvic discomfort and pain.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;hr /&gt;
&lt;div class=&quot;article-content-section&quot;&gt;
&lt;h3 id=&quot;references&quot; class=&quot;reg&quot;&gt;References&lt;/h3&gt;
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&lt;/ol&gt;
&lt;/div&gt;

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