&lt;header class=&quot;bg-primary-header border-b border-gray-100&quot; role=&quot;banner&quot;&gt;
&lt;div class=&quot;container pb-8 lg:pb-16&quot;&gt;&lt;header class=&quot;bg-primary-header border-b border-gray-100&quot; role=&quot;banner&quot;&gt;
&lt;div class=&quot;container pb-8 lg:pb-16&quot;&gt;
&lt;div class=&quot;block-space&quot;&gt;
&lt;div class=&quot;block-space&quot;&gt;
&lt;div class=&quot;relative&quot;&gt;
&lt;div class=&quot;text-sm sm:text-base absolute top-0 left-0 w-full h-full bg-black text-white flex flex-col justify-center items-center&quot; data-js-target=&quot;gc_block_1906&quot;&gt;
&lt;div class=&quot;font-semibold px-2 md:px-4 lg:px-0 mb-4 lg:mb-8 lg:w-2/3 text-center prose&quot;&gt;
&lt;h1&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Lymphogranuloma venereum treatment guidelines&lt;/strong&gt;&lt;/span&gt;&lt;/h1&gt;
&lt;hr /&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Lymphogranuloma venereum is also known as LGV. &lt;a href=&quot;https://www.pulse-clinic.com.sg/lymphogranuloma-venereum-lgv&quot;&gt;Lymphogranuloma venereum (LGV)&lt;/a&gt; is a genital infection caused by the less common serovars of Chlamydia trachomatis (L1, L2, L3).&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;strong&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;Causes of LGV&lt;/span&gt;&lt;/strong&gt;&lt;/h2&gt;
&lt;ol&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #99ccff;&quot;&gt;Chlamydia trachomatis serovars L1, L2, and L3.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #99ccff;&quot;&gt;The L2 serovar has predominated among LGV cases in MSM.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #99ccff;&quot;&gt;LGV is uncommon in developed countries, however, cases have increasingly occurred among MSM where it mainly causes rectal infection.&lt;/span&gt;&lt;/li&gt;
&lt;/ol&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Clinical presentation&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #99ccff;&quot;&gt;Can lead to proctitis with symptoms such as anorectal pain, discharge, tenesmus, bleeding, and constipation. In some cases, this can be severe and chronic, mimicking inflammatory bowel disease.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #99ccff;&quot;&gt;Asymptomatic cases of rectal LGV can also occur.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #99ccff;&quot;&gt;Less commonly, LGV can also cause genital ulceration with inguinal bubo (abscess) formation.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #99ccff;&quot;&gt;MSM who have a positive anal chlamydia test should be assessed for symptoms of proctitis. Refer to proctitis treatment guidelines.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #99ccff;&quot;&gt;MSM who present with symptoms of proctitis should be tested for chlamydia, gonorrhea, syphilis, and herpes using an anal swab.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #99ccff;&quot;&gt;Men who are asymptomatic contacts of LGV should be screened for chlamydia with urine and an anal swab.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;Diagnosis&lt;/span&gt;&lt;/h2&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;block-space&quot;&gt;
&lt;div class=&quot;block-space prose  &quot;&gt;
&lt;table class=&quot;table&quot; style=&quot;margin-left: auto; margin-right: auto; height: 281px;&quot; border=&quot;1&quot; width=&quot;922&quot;&gt;
&lt;thead&gt;
&lt;tr&gt;
&lt;th style=&quot;text-align: left; width: 136.55px;&quot; scope=&quot;col&quot;&gt;Test&lt;/th&gt;
&lt;th style=&quot;text-align: left; width: 162.1px;&quot; scope=&quot;col&quot;&gt;Site/ Specimen&lt;/th&gt;
&lt;th style=&quot;text-align: left; width: 604.55px;&quot; scope=&quot;col&quot;&gt;Comments&lt;/th&gt;
&lt;/tr&gt;
&lt;/thead&gt;
&lt;tbody&gt;
&lt;tr&gt;
&lt;td style=&quot;width: 136.55px;&quot;&gt;NAAT&lt;/td&gt;
&lt;td style=&quot;width: 162.1px;&quot;&gt;
&lt;p&gt;Swab&lt;/p&gt;
&lt;p&gt;Aspirated fluid from inguinal buboes&lt;/p&gt;
&lt;/td&gt;
&lt;td style=&quot;width: 604.55px;&quot;&gt;The LGV serovars can specifically be identified through genotyping of the chlamydia positive sample; however, not all laboratories are able to perform genotyping.&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
&lt;td style=&quot;width: 136.55px;&quot;&gt;Serology for&amp;nbsp;&lt;em&gt;C. trachomatis&lt;/em&gt;&lt;/td&gt;
&lt;td style=&quot;width: 162.1px;&quot;&gt;Blood&lt;/td&gt;
&lt;td style=&quot;width: 604.55px;&quot;&gt;
&lt;p&gt;Can sometimes assist in the diagnosis of LGV, such as when the rectal swab is negative or if it is not possible to amplify the omp1 gene.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;High antibody titres are often found with LGV, which is not usually the case with uncomplicated genital chlamydial infection.&lt;/p&gt;
&lt;p&gt;Serology does not, however, distinguish between LGV and non-LGV serovars.&lt;/p&gt;
&lt;/td&gt;
&lt;/tr&gt;
&lt;/tbody&gt;
&lt;/table&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;block-space&quot; style=&quot;text-align: left;&quot;&gt;
&lt;div class=&quot;prose&quot;&gt;
&lt;h2&gt;Management&lt;/h2&gt;
&lt;/div&gt;
&lt;div class=&quot;block-space prose  &quot;&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;Index patient&lt;/span&gt;&lt;/h3&gt;
&lt;table class=&quot;table&quot; style=&quot;height: 201px;&quot; border=&quot;1&quot;&gt;
&lt;thead&gt;
&lt;tr style=&quot;height: 18px;&quot;&gt;
&lt;th style=&quot;height: 18px;&quot; scope=&quot;col&quot;&gt;Condition&lt;/th&gt;
&lt;th style=&quot;height: 18px;&quot; scope=&quot;col&quot;&gt;Recommended&lt;/th&gt;
&lt;th style=&quot;height: 18px;&quot; scope=&quot;col&quot;&gt;Extra comments&lt;/th&gt;
&lt;/tr&gt;
&lt;/thead&gt;
&lt;tbody&gt;
&lt;tr style=&quot;height: 183px;&quot;&gt;
&lt;td style=&quot;height: 183px;&quot;&gt;LGV&lt;/td&gt;
&lt;td style=&quot;height: 183px;&quot;&gt;
&lt;p&gt;&lt;strong&gt;Doxycycline 100mg PO, twice daily for 21 days&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;OR&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Azithromycin 1g PO, once per week for 3 doses.&lt;/strong&gt;&lt;/p&gt;
&lt;/td&gt;
&lt;td style=&quot;height: 183px;&quot;&gt;
&lt;p&gt;Doxycycline is preferred over azithromycin as clinical data are lacking for azithromycin.&lt;/p&gt;
&lt;p&gt;&lt;abbr style=&quot;box-sizing: border-box; border-width: 0px 0px 1px; border-style: dotted; border-color: rgb(67 56 202 / var(--tw-border-opacity)); --tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-scroll-snap-strictness: proximity; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: rgb(59 130 246 / 0.5); --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; filter: initial !important; --tw-border-opacity: 1; --tw-text-opacity: 1; color: rgb(67 56 202 / var(--tw-text-opacity));&quot; data-tippy-content=&quot;&amp;lt;p&amp;gt;Men who have sex with men&amp;lt;/p&amp;gt;&quot;&gt;MSM&lt;/abbr&gt;&amp;nbsp;who present with symptomatic proctitis that is positive for rectal&amp;nbsp;&lt;em&gt;C. trachomatis&lt;/em&gt;&amp;nbsp;should be treated presumptively for LGV, irrespective of the LGV genotype result which may not be available for several weeks.&lt;/p&gt;
&lt;p&gt;Sometimes LGV can be more severe. In these cases, more prolonged treatment or treatment with alternative antibiotics may be required. This should be discussed with a senior clinician.&amp;nbsp;&lt;/p&gt;
&lt;/td&gt;
&lt;/tr&gt;
&lt;/tbody&gt;
&lt;/table&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;block-space&quot;&gt;
&lt;div class=&quot;prose&quot; style=&quot;text-align: left;&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;div class=&quot;block-space prose  &quot;&gt;
&lt;p style=&quot;text-align: left;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Contact tracing &amp;amp; partner management&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #99ccff;&quot;&gt;Contact tracing for LGV should be initiated.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;All asymptomatic sexual partners of men with LGV should be screened for LGV and &lt;/span&gt;&lt;strong&gt;offered treatment with Doxycycline 100mg orally twice daily for 21 days.&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: left;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/header&gt;&lt;/div&gt;
&lt;/header&gt;

&lt;div class=&quot;md:flex container&quot;&gt;
&lt;div class=&quot;md:w-1/3&quot; role=&quot;complementary&quot;&gt;
&lt;div class=&quot;md:ml-2 lg:ml-4 xl:ml-12 -sidebar&quot;&gt;
&lt;div class=&quot;block-space prose&quot;&gt;
&lt;div class=&quot;space-y-2&quot;&gt;
&lt;p style=&quot;text-align: center;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;text-align: center;&quot;&gt;&lt;a href=&quot;https://www.pulse-clinic.com/booking&quot;&gt;&lt;img src=&quot;https://cms.pulse-clinic.com/Files/Booking%20an%20appointment%20at%20PULSE%20CLINIC.png&quot; width=&quot;300&quot; height=&quot;37&quot; /&gt;&lt;/a&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: center;&quot;&gt;&lt;strong&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Contact us at&amp;nbsp;&lt;/span&gt;&lt;a href=&quot;mailto:info.bkk@pulse-clinic.com&quot;&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;info.bkk@pulse-clinic.com&lt;/span&gt;&lt;/a&gt; &lt;span style=&quot;color: #99ccff;&quot;&gt;or chat on your preferred platform:&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: center;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://wa.me/66652371936&quot;&gt;&lt;img src=&quot;https://cms.pulse-clinic.com/Files/WhatsApp.png&quot; width=&quot;48&quot; height=&quot;82&quot; /&gt;&lt;span style=&quot;color: #ffffff;&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;/a&gt;&lt;/strong&gt;&lt;strong&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;a href=&quot;https://wa.me/66652371936&quot;&gt;+66 65 237 1936&lt;/a&gt;&amp;nbsp;&lt;/span&gt;&amp;nbsp;&amp;nbsp;&lt;/strong&gt;&lt;strong&gt;&lt;a href=&quot;line://ti/p/@946svqfh&quot;&gt;&lt;img src=&quot;https://cms.pulse-clinic.com/Files/line-logo.png&quot; width=&quot;50&quot; height=&quot;85&quot; /&gt; &lt;span class=&quot;w-30 inline-block px-2 mt-3&quot;&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt; @PULSEClinic&lt;/span&gt;&lt;/span&gt;&lt;/a&gt;&amp;nbsp; &lt;/strong&gt;&lt;strong&gt;&lt;a href=&quot;weixin://dl/chat?pulseclinic&quot;&gt;&lt;img src=&quot;https://cms.pulse-clinic.com/Files/WeChat_App_Icon.png&quot; width=&quot;50&quot; height=&quot;85&quot; /&gt;&lt;/a&gt;&amp;nbsp;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;a href=&quot;weixin://dl/chat?pulseclinic&quot;&gt;&lt;span class=&quot;w-30 inline-block px-2 mt-3&quot;&gt;PulseClinic&lt;/span&gt;&lt;/a&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Buy Apretude (Injectable HIV PrEP) Singapore

Buy Apretude (Injectable HIV PrEP) Philippines (Manila, Cebu, Clark-Angeles)

Lymphogranuloma venereum LGV treatment guidelines