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Fetomaternal Bleed, Flow Cytometry, Blood

Fetomaternal Bleed, Flow Cytometry, Blood

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Overview

In hemolytic disease of the newborn, fetal red blood cells are coated with maternal IgG alloantibodies targeting paternal antigens absent on maternal cells. This leads to accelerated cell destruction before and after birth, with varying clinical severity. Detection may require serological testing of seemingly healthy infants. Pregnancy triggers immunization via fetomaternal hemorrhage (FMH), occurring in up to 75% of pregnancies, often around delivery. Rh immune globulin (RhIG) is administered to Rh-negative mothers carrying Rh-positive fetuses to prevent maternal immune response. RhIG dosage depends on FMH volume, occurring during various obstetric procedures and trauma.

 


 

METHOD NAME

Flow Cytometry

 

AVAILABILITY

TBC

 

REPORTING NAME

Fetomaternal Bleed,Flow Cytometry,B

 

ALIASES

Fetal Hemoglobin

Fetal Maternal Bleed

Fetal Maternal Erythrocyte Distribution, Blood

Fetal Red Cells for Fetal Maternal Erythrocyte Distribution

Fetal-Maternal Erythrocyte Differentiation

Kleihauer Acid Elution (Fetal RBC's)

Kleihauer-Betke

Maternal Erythrocyte Diff

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