&lt;h2&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;Overview&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Evaluating patients with suspected hereditary bleeding disorders, considering family history and initial lab results indicating deficiencies in clotting factors or von Willebrand disease. Confirming the diagnosis involves identifying genetic mutations within six associated genes, understanding the molecular basis of the disorder, and providing genetic counseling. Prognosis and risk assessment rely on genotype-phenotype correlations, while carrier testing is recommended for close relatives of affected individuals.&lt;/span&gt;&lt;/p&gt;
&lt;hr /&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;WHAT IS IT USED FOR?&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Assessing inherited bleeding issues in patients with indications of a familial history of such conditions and preliminary lab findings pointing to deficiencies in factors VII, VIII, IX, or XI, or von Willebrand disease.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Confirming the presence of an inherited bleeding disorder by pinpointing a known or suspected genetic mutation within six genes linked to various bleeding disorders.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Identifying specific genetic mutations within these genes to understand the precise molecular defect underlying a patient&#39;s bleeding disorder diagnosis.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Pinpointing the causative genetic mutation for genetic counseling.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Predicting prognosis and assessing risk based on correlations between genotype and phenotype.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Performing carrier testing for close relatives of individuals diagnosed with an inherited bleeding disorder.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;METHOD NAME&lt;br /&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Sequence Capture and Targeted Next-Generation Sequencing (NGS) followed by Polymerase Chain Reaction (PCR) and Sanger Sequencing&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;&lt;br /&gt;AVAILABILITY&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;REPORTING NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;div id=&quot;ReportingName-value&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Bleeding Focused Gene Panel, NGS&lt;/span&gt;&lt;/div&gt;
&lt;h3&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;OTHER NAME&lt;/strong&gt;&lt;/span&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;div class=&quot;container&quot;&gt;
&lt;div class=&quot;row&quot;&gt;
&lt;div class=&quot;col-12 col-sm-12 col-md-12&quot;&gt;
&lt;div class=&quot;tab-component&quot;&gt;
&lt;div class=&quot;tab-content-wrapper&quot;&gt;
&lt;div id=&quot;tabcontent-Overview&quot; class=&quot;tab-content-item active&quot;&gt;
&lt;div id=&quot;aliases-value&quot;&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;NextGen Sequencing Test&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Hereditary bleeding disorder&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Bleeding diathesis&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Abnormal bleeding&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Factor VII deficiency&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;F7D&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;HA&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Hemophilia A&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Factor VIII deficiency&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Christmas Disease&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Factor FIX deficiency&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;FIX Padua&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;HB&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Hemophilia B&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Hemophilia B Leyden&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Hemophilia C&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Factor XI deficiency&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Plasma thromboplastin antecedent deficiency&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;PTA&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Rosenthal syndrome&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Bernard-Soulier syndrome&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Mild macrothrombocytopenia&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Platelet-type von Willebrand disease&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;von Willebrand factor&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;von Willebrand disease&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

&lt;h3 id=&quot;SpecimenType-title&quot;&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN TYPE&lt;/strong&gt;&amp;nbsp;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Whole Blood&lt;br /&gt;&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SHIPPING INSTRUCTIONS&lt;br /&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;div class=&quot;flex-1 overflow-hidden&quot;&gt;
&lt;div class=&quot;react-scroll-to-bottom--css-ffwkx-79elbk h-full&quot;&gt;
&lt;div class=&quot;react-scroll-to-bottom--css-ffwkx-1n7m0yu&quot;&gt;
&lt;div class=&quot;flex flex-col text-sm pb-9&quot;&gt;
&lt;div class=&quot;w-full text-token-text-primary&quot; dir=&quot;auto&quot; data-testid=&quot;conversation-turn-7&quot;&gt;
&lt;div class=&quot;px-4 py-2 justify-center text-base md:gap-6 m-auto&quot;&gt;
&lt;div class=&quot;flex flex-1 text-base mx-auto gap-3 juice:gap-4 juice:md:gap-6 md:px-5 lg:px-1 xl:px-5 md:max-w-3xl lg:max-w-[40rem] xl:max-w-[48rem] group final-completion&quot;&gt;
&lt;div class=&quot;relative flex w-full flex-col agent-turn&quot;&gt;
&lt;div class=&quot;flex-col gap-1 md:gap-3&quot;&gt;
&lt;div class=&quot;flex flex-grow flex-col max-w-full&quot;&gt;
&lt;div class=&quot;min-h-[20px] text-message flex flex-col items-start gap-3 whitespace-pre-wrap break-words [.text-message+&amp;amp;]:mt-5 overflow-x-auto&quot; dir=&quot;auto&quot; data-message-author-role=&quot;assistant&quot; data-message-id=&quot;51364005-ca87-4f44-9ae9-16e243c2b60c&quot;&gt;
&lt;div class=&quot;markdown prose w-full break-words dark:prose-invert light&quot;&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN COLLECTION&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Container/Tube:&lt;/strong&gt; Lavender top containing EDTA&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Specimen Volume:&lt;/strong&gt; 3 mL&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;Collection Instructions:&lt;/strong&gt; &lt;/span&gt;&lt;/p&gt;
&lt;ol&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Gently rotate the tube multiple times to thoroughly mix the blood.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Submit the whole blood sample in its original tube. Avoid dividing it into separate portions.&lt;/span&gt;&lt;/li&gt;
&lt;/ol&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

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Bleeding Disorders, Focused Gene Panel, Next-Generation Sequencing, Varies