
Bile Acids, Fractionated and Total, Serum
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Overview
This assay is valuable for measuring various bile acid constituents in serum samples, particularly useful in monitoring patients undergoing bile acid therapy. It aids in evaluating liver function, detecting hepatic dysfunction due to chemical or environmental damage, and indicating improvements in liver histology in hepatitis C patients responding to interferon treatment. Additionally, it can help diagnose intrahepatic cholestasis of pregnancy.
WHAT IS IT USED FOR?
- Assessing the levels of bile acid components, including both conjugated and unconjugated forms, in serum samples.
- Tracking individuals undergoing treatment with bile acids like cholic acid, deoxycholic acid, or ursodeoxycholic acid.
- Assisting in assessing liver function and detecting changes in liver health before more severe symptoms like jaundice develop.
- Identifying liver impairment caused by chemical or environmental damage.
- Showing improvement in liver tissue structure in chronic hepatitis C patients who respond positively to interferon therapy.
- Suggesting pregnancy-related obstruction of bile flow within the liver.
- This test is not effective for diagnosing peroxisomal biogenesis disorders or congenital abnormalities related to bile acid metabolism.
METHOD NAME
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
AVAILABILITY
TBC
REPORTING NAME
Bile Acids, Fractionated and Tot, S
OTHER NAME
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Bile Acid