&lt;h2&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;Overview&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;The Achaete-Scute Homolog 1 (ASCL1) Immunostain, Technical Component Only, is utilized for detecting ASCL1 presence. Reflex tests include IHTOI for initial and additional technical components involving immunohistochemical (IHC) staining. The testing algorithm automatically applies the bill-only test IDs (IHTOI and IHTOA) based on the technical component performed.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;The method employed is Immunohistochemistry (IHC). Specimens required are tissue samples, with preferred submission using an Immunostain Technical Only Envelope. The test focuses solely on the technical execution of the stain, without pathologist interpretation. Shipping instructions advise affixing provided labels onto the transport container. Specimens must meet specific criteria for acceptance and stability.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;hr /&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;WHAT IS IT USED FOR?&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Detection of achaete-scute homolog 1 (ASCL1) presence.&lt;/span&gt;&lt;/p&gt;

&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;REFLEX TESTS&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;IHTOI &amp;ndash; IHC Initial, Tech Only (Not Available Separately), (Not Always Performed)&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;IHTOI &amp;ndash; &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;IHC Additional, Tech Only&lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; (Not Available Separately), (Not Always Performed)&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;TESTING ALGORITHM&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;If only the initial technical component involves immunohistochemical (IHC) staining, the suitable bill-only test ID (IHTOI) will be automatically applied and billed. For each additional technical component that solely includes IHC staining, an extra bill-only test ID (IHTOA) will be reflexively applied and charged.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;METHOD NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Immunohistochemistry (IHC)&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;AVAILABILITY&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;REPORTING NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;h4&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;ASCL1 (hASH1) IHC, Tech Only&lt;/span&gt;&lt;/h4&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;ALIASES&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;ACSL1&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;hASH1&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;ISASCL1IHCTO&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN TYPE&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;h4&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;TECHONLY&lt;/span&gt;&lt;/h4&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;ORDERING GUIDANCE&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;This test exclusively covers the technical execution of the stain, without any interpretation by a pathologist. If there is a need for diagnostic consultation by a pathologist, please request PATHC / Pathology Consultation.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SHIPPING INSTRUCTIONS&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Affix the green pathology address label and the pink Immunostain Technical Only label provided in the kit onto the exterior of the transport container.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN REQUIRED&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Supplies: Immunostain Technical Only Envelope (T693)&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Specimen Type: Tissue&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Container/Tube: Immunostain Technical Only Envelope&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Preferred: 2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Acceptable: Formalin-fixed, paraffin-embedded (FFPE) tissue block&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN MINIMUM VOLUME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;See Specimen Required&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;REJECT DUE TO&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Wet/frozen tissue&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Cytology smears&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Nonformalin fixed tissue&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Nonparaffin-embedded tissue&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;Noncharged slides&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;font-weight: 400; color: #808080;&quot;&gt;ProbeOn slides&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN STABILITY INFORMATION&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;TECHONLY &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;&amp;ndash; &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Ambient (preferred)&lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; &amp;ndash; TBC days&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot; aria-level=&quot;1&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;TECHONLY&lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; &amp;ndash; &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Refrigerated &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;&amp;ndash; TBC days&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;